McGouran Laboratory

Congratulations to Joanna on being promoted to Associate Professor!

The laboratory was awarded SFI Frontiers for the Future funding to find new ways of studying enzyme activity using radical chemistry.

Our new paper on rapid diazotranfer for selective lysine labelling has been published in Organic & Biomolecular Chemistry! Read it here

Welcome to our new PhD students Ailish and Ilaria, masters student Fayanne, Erasmus student Gemma, and senior sophister project students Marina, Layla, and Adithi.

Congratulations to Fayanne and Ailish for obtaining IRC funding for a masters and a PhD respectively

Our new paper on modified oligonucleotides to study DNA damage repair enzyme SNM1A has just been accepted in ChemBioChem! Read it here

Our new paper on probing the metalloproteome has just come out in RSC Chemical Biology! Read it here

Congratulations to Dr Susannah Calvert who passed her PhD viva today. Susie is the 6th PhD student to graduate from the McGouran group.

Scholarship or research achievement of a high order is the primary qualification for Fellowship, coupled with evidence of the candidate's contribution to the academic life of the College and an effective record in teaching.

Congratulations to Ellen who was awarded the Institute of Chemistry of Ireland postgraduate award today. Only one award is given across all of chemistry in Ireland per year, with demonstrated excellence in research through publications.

Congratulations to Dr Ellen Fay who passed her PhD viva today. Ellen is the 5th PhD student to graduate from the McGouran group.

Congratulations to Dr Sean McKenna who passed his PhD viva today. Sean is the 4th PhD student to graduate from the McGouran group.

Joanna will give a seminar on some of the groups latest work at the University of York

Joanna will give a seminar on some of the groups latest work at Durham University 

Joanna will give a seminar on some of the groups latest work at Newcastle University 

Congratulations Julie and Ellen for winning the W.H.A. Macintosh Prize  in 2023 and 2019 as students with the highest marks going directly into a PhD in TCD chemistry

Welcome back to Julie, who is rejoining the group as our new PhD student. Also welcome to Denise from the University of Heidelberg, who will be completing a Masters project in the group.

And finally welcome to Blathnait, Aparna and Rebecca who will be joining the lab this term to complete their senior sophister projects.

Our News and Views article on Rapid capture of small peptide binders is out now in Nature Reviews Chemistry! Read it here.

Congratulations to Ellen for winning a poster prize at the RSC organic chemistry community meeting Ireland!

The Royal Society of Chemistry Organic Chemistry Community meeting will be organized by Joanna in Trinity College Dublin this year

Congratulations to Sean for his award for Best Oral Presentation Prize at the 74th Irish Universities Chemistry Research Colloquium!

A new paper in collaboration with the Imperiali group in MIT Deploying solid-phase synthesis to access thymine-containing nucleoside analogs that inhibit DNA repair nuclease SNM1A is out now in OBC! Read it here.

Congratulations to Sean for winning a speakers prize at the Irish Mass Spec Society annual meeting!

Oisin will be joining us over the summer from the University of Cambridge to work on electrochemical modification of proteins.

Congratulations to Sean for winning a speakers prize at the RSC chemical biology and biological chemistry Group Post-Grad symposium  in Oxford!

Our new paper on two-Step Validation Approach for Tools to Study the DNA Repair Enzyme SNM1A is out now in ChemBioChem!

This invited article is part of the CheBioTalents collection Read it here.

Joanna will give a seminar on some of the groups latest work at the University of Oxford as part of the Chemistry department's annual poster day

Joanna co-organized this Royal Society of Chemistry conference with Dr Stephen Cochrane in Queens's University Belfast 

Our new paper on the effect of nucleobase modification on nucleoside inhibitors of SNM1A is out now in Results in Chemistry! Read it here.

Congratulations to Eva & Neil on graduation of their PhDs, two years delayed!

An update on the groups latest results in modified nucleoside synthesis at the carbohydrate group meeting in Queens University Belfast.

Congratulations to Mark on his graduation from his PhD!

Congratulations to Sean who has received an EMBO fellowship to spend 6 months at Leiden Univeristy in Prof. Sander van Kasteren's Lab!

Joanna will give a seminar on some of the groups latest work at the University of Galway

Welcome to the group to Andre, our new postdoc who will be working on radical probes for deubiquitinating enzymes. Also welcome to Dario, Julie and Melissa who will be joining the lab this term to complete their senior sophister projects.

Congratulations to Sean for winning a poster prize at Chemical Biology Ireland 2022 at the University College Dublin

Congratulations to Dr Mark Berney for passing his PhD viva today-the groups first in person viva!

Congratulations to Sean for winning a poster prize at Medicinal Chemistry Ireland 2022 at the University of Galway 

Congratulations to Sean for winning a "best talk" prize for his 3rd DUBChem year PhD talk

Welcome to the group to Lorenzo, who is joining the lab to complete his Masters thesis for the University of Siena

The lab has been awarded a collaborative grant with Queens University Belfast to investigate new probes and methods of inhibitor profiling for deubiquitinating enzymes

Our new paper on the effect of 5' phosphorylation on nucleoside inhibitors of SNM1A is out now in ChemMedChem! Read it here.

Joanna will give a (virtual) seminar on some of the groups latest work at the University of Pennsylvania

Our new review on activation of probes for protein profiling is out now in ACS Chemical Biology! Read it here.

Mark starts his Fulbright award at the University of Chicago with Professor Bryan Dickinson in September.

Ben and Mary will be joining the lab this term to complete their senior sophister projects.

Our new paper on nucleoside inhibitors of SNM1A and their correlation to zinc binding strength is out now in Bioorganic and Medicinal Chemistry! Read it here.

Welcome to the group to Tomasz, our new PhD student, who will be working on radical chemistry for protein labeling.

Joanna gives an overview to the groups research aims. Watch it here.

Joanna talks about some of the groups latest work. Links to the talks available here.

Ben will be joining the lab over the summer to explore new zinc binding groups and their potential as enzyme inhibitors.

Our new paper on the use (and limitations!) of Eosin Y for radical initiated protein profiling is out now in Organic and Biomolecular Chemistry! Read it here.

Congratulations to Neil who passed his viva today with flying colors and is soon off to Germany to postdoc in chemical biology.

Our new paper on malonates as zinc binding groups to inhibit 5'exonuclease SNM1A is out now in Molecules! Read it here.

Welcome to the group to Ailish and Fergus who will be completing their 4th yea projects in the group.

Mark will present some of his latest results at the Centre for Synthesis and Chemical Biology Annual Symposium

Congratulations to Eva for passing her PhD viva today! Eva is the first PhD student to graduate from the group.

Welcome to the group to Connor and Valerio who are embarking on PhDs in bioresponsive systems and activity based probes.

Check out the groups article no female Nobel prize laureates in chemistry. Read it here. 

Mark presents his PhD results

Ellen presents some of her latest work at the online RSC Nucleic Acids Forum